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Curly hair is most susceptible to damage from chemical treatments primarily due to its unique structure and composition. The natural curl pattern in this type of hair is often the result of the shape of the hair follicle and the distribution of disulfide bonds within the hair strands. These bonds are critical for maintaining the integrity of the hair’s shape.

When chemical treatments, such as relaxers or perms, are applied to curly hair, they can disrupt these bonds. The chemicals work by breaking disulfide bonds to alter the hair's structure, which can lead to increased porosity and weakened strands if not done carefully or if the hair is already damaged.

In addition, curly hair tends to be drier than straight hair due to its shape, which makes it more challenging for natural oils produced by the scalp to travel down the hair shaft. This lack of moisture can make the hair more vulnerable to breakage when exposed to harsh chemicals. Therefore, special care and tailored treatment options are essential to minimize damage when working with curly hair in the context of chemical processes.